Atomoxetine is the only widely used non-stimulant medicine approved for ADHD in adults and children. It works differently from stimulants and can help when stimulants cause side effects or aren’t an option.
Atomoxetine blocks the reuptake of norepinephrine in the brain, which improves attention and reduces impulsivity for many people. Unlike stimulant drugs, it usually takes several weeks to build full effect — expect to see steady improvement within 2 to 6 weeks, and sometimes longer. Don’t stop early if you don’t feel better right away; talk with your prescriber about adjusting dose before giving up.
Your doctor will pick a starting dose based on age and weight. Adults often start around 40 mg daily and may increase to 80 mg; some patients need up to 100 mg under supervision. Children are dosed per kilogram of body weight; follow pediatric guidance closely. Take atomoxetine once or twice a day with food to reduce stomach upset. If you miss a dose, take it as soon as you remember that day — don’t double the next dose.
Common side effects include nausea, dry mouth, decreased appetite, insomnia, and mild mood swings. Some people notice a small rise in heart rate or blood pressure; check these during follow-up visits. Rarely, atomoxetine can cause liver problems or worsen mood, including thoughts of self-harm in children and adolescents. Report yellowing skin, dark urine, or new suicidal thoughts to a clinician right away.
Avoid atomoxetine with monoamine oxidase inhibitors (MAOIs). Drugs that block CYP2D6 — like fluoxetine or paroxetine — can raise atomoxetine levels and may require a lower dose. Tell your doctor about all prescriptions, over‑the‑counter meds, and supplements. If you have heart disease, high blood pressure, liver problems, or a history of mood disorders, discuss risks and monitoring plans.
Atomoxetine is prescription‑only in many places. If you shop online, use pharmacies that require a valid prescription, show clear contact info, and carry verification seals. Avoid sellers offering huge discounts without asking for a prescription. When shipping internationally, check customs rules and be ready for delays. Keep medication in its original container and store at room temperature away from moisture.
Quick checklist before you start: 1) Confirm diagnosis and discuss goals with your prescriber. 2) Review your medical history and current medications. 3) Plan for blood pressure and mood checks after starting. 4) Use a reliable pharmacy that requires a prescription.
Pregnancy and breastfeeding: data are limited. Talk with your doctor if you're pregnant, planning pregnancy, or breastfeeding — they will weigh benefits and risks and may suggest alternatives. Keep a symptom diary for the first weeks to share with your clinician. Ask questions and follow up.